Prof. Ziyaad Dangor

Clinical Research Director


Associate Professor Ziyaad Dangor is the clinical research director at the world-renowned Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit (VIDA). He is a paediatric pulmonologist at the Chris Hani Baragwanath Academic Hospital in the Department of Paediatrics and Child Heath at the University of the Witwatersrand. His qualifications include MBBCh (Wits), MMed (Wits), FCPaeds (SA), CertPulm (SA) and PhD (Wits).

Ziyaad is a National Research Foundation Y1-rated scientist, and has undertaken investigator-initiated, original research using a range of clinical, epidemiological and laboratory-based research techniques to establish a successful research output, including the publication of cited papers in high-impact factor journals in the field. For a complete list of published work, visit:

Ziyaad is actively involved in undergraduate and postgraduate teaching at the University of Witwatersrand. He is the chair of the South African Paediatric Association, and an examiner in the College of Paediatricians of South Africa. He is also an instructor with the Advanced Paediatric Life Support Group.


Rees CA; Igunza KA; Madewell ZJ; Akelo V; Onyango D; El Arifeen S; Gurley ES; Hossain MZ; Rahman A; Alam M; Scott JAG; Assefa N; Madrid L; Belachew A; Leulseged H; Kotloff KL; Sow SO; Tapia MD; Keita AM; Sidibe D; Sitoe A; Varo R; Ajanovic S; Bassat Q; Mandomando I; Tippett Barr BA; Ogbuanu I; Cain CJ; Bassey IA; Luke R; Gassama K; Madhi S; Dangor Z; Mahtab S; Velaphi S; du Toit J; Mutevedzi PC; Blau DM; Breiman RF; Whitney CG, 2023. Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) network.  EClinicalMedicine 63:102198

Birkhead M; Otido S; Mabaso T; Mopeli K; Tlhapi D; Verwey C; Dangor Z, 2023. Ultrastructure for the diagnosis of primary ciliary dyskinesia in South Africa, a resource-limited setting.  Front Pediatr 11:1247638

Mopeli K; Mabaso T; Alli N; Dangor Z; Verwey C, 2023. Diffuse alveolar haemorrhage in children hospitalised in a tertiary‑level hospital: A retrospective descriptive study.  Afr J Thorac Crit Care Med 29.

Dangor Z; Seale AC; Baba V; Kwatra G, 2023. Early-onset group B streptococcal disease in African countries and maternal vaccination strategies.  Front Public Health 11:1214844

Dangor Z; Lala S; Verwey C; Reubenson G; White D; Moore D; Jeena P; Masekela R; Zar H, 2023. Bronchiolitis versus bronchopneumonia: navigating antibiotic use within the LRTI spectrum.  S Afr Med J 113(6):20-23

Verwey C; Ramocha L; Laubscher M; Baillie V; Nunes M; Gray D; Hantos Z; Dangor Z; Madhi S, 2023. Pulmonary sequelae in 2-year-old children after hospitalisation for respiratory syncytial virus lower respiratory tract infection during infancy: an observational study.  BMJ Open Respir Res 10.

Izu A; Nunes MC; Solomon F; Baillie V; Serafin N; Verwey C; Moore DP; Laubscher M; Ncube M; Olwagen C; Dangor Z; Madhi SA, 2023. All-cause and pathogen-specific lower respiratory tract infection hospital admissions in children younger than 5 years during the COVID-19 pandemic (2020-22) compared with the pre-pandemic period (2015-19) in South Africa: an observational study.  Lancet Infect Dis 23(9):1031-1041

Dangor Z; Kwatra G; Pawlowski A; Fisher PB; Izu A; Lala SG; Johansson-Lindbom B; Madhi SA, 2023. Association of infant Rib and Alp1 surface protein N-terminal domain immunoglobulin G and invasive Group B Streptococcal disease in young infants.  Vaccine 41(10):1679-1683

Otido S; Dangor Z; Zanini A; Harrison D, 2022. Giant thymolipoma in a child: The silent chest mass.  Afr J Thorac Crit Care Med 28.

Verwey C; Gray DM; Dangor Z; Ferrand RA; Ayuk AC; Marangu D; Kwarteng Owusu S; Mapani MK; Goga A; Masekela R, 2022. Bronchiectasis in African children: Challenges and barriers to care.  Front Pediatr 10:954608

Paul P; Chandna J; Procter SR; Dangor Z; Leahy S; Santhanam S; John HB; Bassat Q; Bramugy J; Bardají A; Abubakar A; Nasambu C; Libster R; Yanotti CS; Seedat F; Horváth-Puhó E; Hossain AKMT; Sadeq-Ur Rahman Q; Jit M; Newton CR; Milner K; Gonçalves BP; Lawn JE, 2022. Neurodevelopmental and growth outcomes after invasive Group B Streptococcus in early infancy: A multi-country matched cohort study in South Africa, Mozambique, India, Kenya, and Argentina.  EClinicalMedicine 47:101358

Gonçalves BP; Procter SR; Paul P; Chandna J; Lewin A; Seedat F; Koukounari A; Dangor Z; Leahy S; Santhanam S; John HB; Bramugy J; Bardají A; Abubakar A; Nasambu C; Libster R; Sánchez Yanotti C; Horváth-Puhó E; Sørensen HT; van de Beek D; Bijlsma MW; Gardner WM; Kassebaum N; Trotter C; Bassat Q; Madhi SA; Lambach P; Jit M; Lawn JE, 2022. Group B streptococcus infection during pregnancy and infancy: estimates of regional and global burden.  Lancet Glob Health 10(6):e807-e819

Car KP; Nakwa F; Solomon F; Velaphi SC; Tann CJ; Izu A; Lala SG; Madhi SA; Dangor Z, 2022. The association between early-onset sepsis and neonatal encephalopathy.  J Perinatol 42(3):354-358

Kufa T; Jassat W; Cohen C; Tempia S; Masha M; Wolter N; Walaza S; von Gottburg A; Govender NP; Hunt G; Shonhiwa AM; Ebonwu J; Ntshoe G; Maruma W; Bapela P; Ndhlovu N; Mathema H; Modise M; Shuping L; Manana PN; Moore D; Dangor Z; Verwey C; Madhi SA; Saloojee H; Zar HJ; Blumberg L, 2022. Epidemiology of SARS-CoV-2 infection and SARS-CoV-2 positive hospital admissions among children in South Africa.  Influenza Other Respir Viruses 16(1):34-47

Harden LM; Leahy S; Lala SG; Paul P; Chandna J; Lowick S; Mbatha S; Jaye T; Laughton B; Ghoor A; Sithole P; Msayi J; Kumalo N; Msibi TN; Madhi SA; Lawn JE; Dangor Z, 2022. South African Children: A Matched Cohort Study of Neurodevelopmental Impairment in Survivors of Invasive Group B Streptococcus Disease Aged 5 to 8 Years.  Clin Infect Dis 74(Suppl_1):S5-S13

Aerts C; Leahy S; Mucasse H; Lala S; Bramugy J; Tann CJ; Madhi SA; Bardají A; Bassat Q; Dangor Z; Lawn JE; Jit M; Procter SR, 2022. Quantifying the Acute Care Costs of Neonatal Bacterial Sepsis and Meningitis in Mozambique and South Africa.  Clin Infect Dis 74(Suppl_1):S64-S69

Chandna J; Liu WH; Dangor Z; Leahy S; Sridhar S; John HB; Mucasse H; Bassat Q; Bardaji A; Abubakar A; Nasambu C; Newton CR; Sánchez Yanotti C; Libster R; Milner K; Paul P; Lawn JE, 2022. Emotional and Behavioral Outcomes in Childhood for Survivors of Invasive Group B Streptococcus Disease in Infancy: Findings From 5 Low- and Middle-Income Countries.  Clin Infect Dis 74(Suppl_1):S35-S43

Alli HD; Ally N; Mayet I; Dangor Z; Madhi SA, 2022. Global prevalence and clinical outcomes of tubercular uveitis: a systematic review and meta-analysis.  Surv Ophthalmol 67(3):770-792

Tebeila ND; Dangor Z; Madhi SA; Cutland C; Groome MJ, 2021. Incidence of febrile seizures and associated factors in children in Soweto, South Africa.  S Afr Med J 111(8):796-802

Mangeni NS; Solomon F; Velaphi S; Izu A; Madhi SA; Dangor Z; Lala SG, 2021. Sepsis in previously healthy neonates discharged home after delivery in Soweto, South Africa.  S Afr Med J 111(5):432-436

Dangor Z; Kwatra G; Izu A; Khan M; Lala SG; Madhi SA, 2021. Infant serotype specific anti-capsular immunoglobulin G antibody and risk of invasive group B Streptococcal disease.  Vaccine 39(47):6813-6816

Mabena FC; Baillie VL; Hale MJ; Thwala BN; Mthembu N; Els T; Serafin N; du Plessis J; Swart P; Velaphi SC; Petersen KL; Wadula J; Govender NP; Verwey C; Moore DP; Moosa FY; Nakwa FL; Maroane BV; Okudo G; Mabaso TM; Dangor Z; Nunes MC; Madhi SA, 2021. Clinical Characteristics and Histopathology of Coronavirus Disease 2019-Related Deaths in African Children.  Pediatr Infect Dis J 40(9):e323-e332

Dangor Z; Verwey C; Lala SG; Mabaso T; Mopeli K; Parris D; Gray DM; Chang AB; Zar HJ, 2021. Lower Respiratory Tract Infection in Children: When Are Further Investigations Warranted?  Front Pediatr 9:708100

Reddy DL; Dangor Z; Lala N; Johnstone J; Maswabi L; Tsitsi JML, 2021. COVID-19 mass vaccination campaign for healthcare workers in a low-resource setting: A clinician-driven initiative.  S Afr Med J 111(7):610-614

Jassat W; Cohen C; Tempia S; Masha M; Goldstein S; Kufa T; Murangandi P; Savulescu D; Walaza S; Bam JL; Davies MA; Prozesky HW; Naude J; Mnguni AT; Lawrence CA; Mathema HT; Zamparini J; Black J; Mehta R; Parker A; Chikobvu P; Dawood H; Muvhango N; Strydom R; Adelekan T; Mdlovu B; Moodley N; Namavhandu EL; Rheeder P; Venturas J; Magula N; Blumberg L, 2021. Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study.  Lancet HIV 8(9):e554-e567

Jassat W; Mudara C; Ozougwu L; Tempia S; Blumberg L; Davies MA; Pillay Y; Carter T; Morewane R; Wolmarans M; von Gottberg A; Bhiman JN; Walaza S; Cohen C, 2021. Difference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study.  Lancet Glob Health 9(9):e1216-e1225

Ealand C; Peters J; Jacobs O; Sewcharran A; Ghoor A; Golub J; Brahmbhatt H; Martinson N; Dangor Z; Lala SG; Kana B, 2021. Detection of Mycobacterium tuberculosis Complex Bacilli and Nucleic Acids From Tongue Swabs in Young, Hospitalized Children.  Front Cell Infect Microbiol 11:696379

Lukhele ST; Kwatra G; Ismail A; Allam M; Dangor Z; Madhi SA, 2021. Investigation of Possible Nosocomial-Associated Invasive Group B Streptococcus Disease Using Whole-Genome Sequencing: A Report of 3 Cases.  J Pediatric Infect Dis Soc 10(8):880-882

Nunes MC; Baillie VL; Kwatra G; Bhikha S; Verwey C; Menezes C; Cutland CL; Moore DP; Dangor Z; Adam Y; Mathivha R; Velaphi SC; Tsitsi M; Aguas R; Madhi SA, 2021. Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Healthcare Workers in South Africa: A Longitudinal Cohort Study.  Clin Infect Dis 73(10):1896-1900

Madhi SA; Izu A; Kwatra G; Jones S; Dangor Z; Wadula J; Moultrie A; Adam Y; Pu W; Henry O; Briner C; Cutland CL, 2021. Association of Group B Streptococcus (GBS) Serum Serotype-Specific Anticapsular Immunoglobulin G Concentration and Risk Reduction for Invasive GBS Disease in South African Infants: An Observational Birth-Cohort, Matched Case-Control Study.  Clin Infect Dis 73(5):e1170-e1180

Mitha M; Pillay M; Moodley JY; Balakrishna Y; Abbai N; Bhagwan S; Dangor Z; Bhigjee AI, 2020. Laboratory diagnosis of tuberculous meningitis in human immunodeficiency virus-seropositive patients: Correlation with the uniform case definition.  S Afr J Infect Dis 35(1):135

Paul P; Procter SR; Dangor Z; Bassat Q; Abubakar A; Santhanam S; Libster R; Gonçalves BP; Madhi SA; Bardají A; Mwangome E; Mabrouk A; John HB; Sánchez Yanotti C; Chandna J; Sithole P; Mucasse H; Katana PV; Koukounari A; Harden LM; Aerts C; Ghoor A; Leahy S; Mbatha S; Lowick S; Lala SG; Bramugy J; Newton C; Hossain AKMT; Sadeq-Ur Rahman Q; Lambach P; Jit M; Lawn JE, 2020. Quantifying long-term health and economic outcomes for survivors of group B Streptococcus invasive disease in infancy: protocol of a multi-country study in Argentina, India, Kenya, Mozambique and South Africa.  Gates Open Res 4:138

Nakwa FL; Lala SG; Madhi SA; Dangor Z, 2020. Neurodevelopmental Impairment at 1 Year of Age in Infants With Previous Invasive Group B Streptococcal Sepsis and Meningitis.  Pediatr Infect Dis J 39(9):794-798

George A; Dangor Z; Lala SG, 2020. Lamenting the changes in clinical bedside paediatric teaching at Chris Hani Baragwanath Academic Hospital: More resources are needed to train effective doctors.  S Afr Med J 110(5):12932

Verwey C; Nunes MC; Dangor Z; Madhi SA, 2020. Pulmonary function sequelae after respiratory syncytial virus lower respiratory tract infection in children: A systematic review.  Pediatr Pulmonol 55(7):1567-1583

Dangor Z; Khan M; Kwatra G; Izu A; Nakwa F; Ramdin T; Fredericks J; Lala SG; Madhi SA, 2020. The Association Between Breast Milk Group B Streptococcal Capsular Antibody Levels and Late-onset Disease in Young Infants.  Clin Infect Dis 70(6):1110-1114

Ji W; Liu H; Madhi SA; Cunnington M; Zhang Z; Dangor Z; Zhou H; Mu X; Jin Z; Wang A; Qin X; Gao C; Zhu Y; Feng X; She S; Yang S; Liu J; Lei J; Jiang L; Liu Z; Li G; Li Q; Deng Q; Gao K; Fang Y, 2019. Clinical and Molecular Epidemiology of Invasive Group B Streptococcus Disease among Infants, China.  Emerg Infect Dis 25(11):2021-2030

McLaren B; Song X; Mate E; Jardine C; Mabaso T; Mammen V; Lala S; Dangor Z; Verwey C, 2019. Chylothorax in a child with rifampicin-resistant tuberculosis.  Afr J Thorac Crit Care Med 25.

Kutsukutsa J; Rankhethoa N; Pillay JS; De Jager JF; Dangor Z; Mahabeer Y, 2019. Streptococcus equi subsp. zooepidemicus and 'Neighbourhood syndrome' -extra-orbitocranial rhinosinusitis with reversible sudden loss of vision- a case report.  BMC Ophthalmol 19(1):117

Makgatho E; Patel F; Solomon F; Groome MJ; Lala SG; Vallabh P; Dangor Z, 2019. The Burden of Acute Diarrheal Disease in Young Hospitalized Urban South African Children Five Years After Rotavirus Vaccine Introduction: A Retrospective Descriptive Study.  Pediatr Infect Dis J 38(7):752-756

Velaphi SC; Westercamp M; Moleleki M; Pondo T; Dangor Z; Wolter N; von Gottberg A; Shang N; Demirjian A; Winchell JM; Diaz MH; Nakwa F; Okudo G; Wadula J; Cutland C; Schrag SJ; Madhi SA, 2019. Surveillance for incidence and etiology of early-onset neonatal sepsis in Soweto, South Africa.  PLoS One 14(4):e0214077

Singh S; Solomon F; Madhi SA; Dangor Z; Lala SG, 2018. An evaluation of the quality of discharge summaries from the general paediatric wards at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa.  S Afr Med J 108(11):953-956

Ghoor A; Mabaso T; Mopeli K; Izu A; Madhi SA; Lala SG; Verwey C; Dangor Z, 2018. Empyema in children hospitalised at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa: A retrospective study.  S Afr Med J 108(12):1055-1058

Price CA; Green-Thompson L; Mammen VG; Madhi SA; Lala SG; Dangor Z, 2018. Knowledge gaps among South African healthcare providers regarding the prevention of neonatal group B streptococcal disease.  PLoS One 13(10):e0205157

Kohli-Lynch M; Russell NJ; Seale AC; Dangor Z; Tann CJ; Baker CJ; Bartlett L; Cutland C; Gravett MG; Heath PT; Ip M; Le Doare K; Madhi SA; Rubens CE; Saha SK; Schrag S; Sobanjo-Ter Meulen A; Vekemans J; O'Sullivan C; Nakwa F; Ben Hamouda H; Soua H; Giorgakoudi K; Ladhani S; Lamagni T; Rattue H; Trotter C; Lawn JE, 2017. Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses.  Clin Infect Dis 65(suppl_2):S190-S199

Madrid L; Seale AC; Kohli-Lynch M; Edmond KM; Lawn JE; Heath PT; Madhi SA; Baker CJ; Bartlett L; Cutland C; Gravett MG; Ip M; Le Doare K; Rubens CE; Saha SK; Sobanjo-Ter Meulen A; Vekemans J; Schrag S, 2017. Infant Group B Streptococcal Disease Incidence and Serotypes Worldwide: Systematic Review and Meta-analyses.  Clin Infect Dis 65(suppl_2):S160-S172

Dangor Z; Nunes MC; Kwatra G; Lala SG; Madhi SA, 2017. Vaccination of HIV-infected pregnant women: implications for protection of their young infants.  Trop Dis Travel Med Vaccines 3:1

Madhi SA; Dangor Z, 2017. Prospects for preventing infant invasive GBS disease through maternal vaccination.  Vaccine 35(35 Pt A):4457-4460

Dzanibe S; Adrian PV; Mlacha SZK; Dangor Z; Kwatra G; Madhi SA, 2017. Reduced Transplacental Transfer of Group B Streptococcus Surface Protein Antibodies in HIV-infected Mother-Newborn Dyads.  J Infect Dis 215(3):415-419

Nishihara Y; Dangor Z; French N; Madhi S; Heyderman R, 2017. Challenges in reducing group B Streptococcus disease in African settings.  Arch Dis Child 102(1):72-77

Mammen VG; Dangor Z; Moore DP; Izu A; Beylis N; Madhi SA, 2017. Hospitalization for Culture-confirmed Pulmonary Tuberculosis in the Era of Childhood Pneumococcal Conjugate Vaccine Immunization.  Pediatr Infect Dis J 36(1):e14-e21

Dangor Z; Cutland CL; Izu A; Kwatra G; Trenor S; Lala SG; Madhi SA, 2016. Temporal Changes in Invasive Group B Streptococcus Serotypes: Implications for Vaccine Development.  PLoS One 11(12):e0169101

Chaya S; Dangor Z; Solomon F; Nzenze SA; Izu A; Madhi SA, 2016. Incidence of tuberculosis meningitis in a high HIV prevalence setting: time-series analysis from 2006 to 2011.  Int J Tuberc Lung Dis 20(11):1457-1462

Dangor Z; Lala SG; Kwatra G; Madhi SA, 2016. Group B Streptococcus: developing a correlate of protection for a vaccine against neonatal infections.  Curr Opin Infect Dis 29(3):262-7

Dangor Z; Kwatra G; Izu A; Adrian P; Cutland CL; Velaphi S; Ballot D; Reubenson G; Zell ER; Lala SG; Madhi SA, 2015. Correlates of protection of serotype-specific capsular antibody and invasive Group B Streptococcus disease in South African infants.  Vaccine 33(48):6793-9

Dangor Z; Kwatra G; Izu A; Adrian P; Cutland CL; Velaphi S; Ballot D; Reubenson G; Zell ER; Lala SG; Madhi SA, 2015. Association between maternal Group B Streptococcus surface-protein antibody concentrations and invasive disease in their infants.  Expert Rev Vaccines 14(12):1651-60

Nan C; Dangor Z; Cutland CL; Edwards MS; Madhi SA; Cunnington MC, 2015. Maternal group B Streptococcus-related stillbirth: a systematic review.  BJOG 122(11):1437-45

Dangor Z; Lala SG; Cutland CL; Koen A; Jose L; Nakwa F; Ramdin T; Fredericks J; Wadula J; Madhi SA, 2015. Burden of invasive group B Streptococcus disease and early neurological sequelae in South African infants.  PLoS One 10(4):e0123014

Dangor Z; Kwatra G; Izu A; Adrian P; van Niekerk N; Cutland CL; Adam Y; Velaphi S; Lala SG; Madhi SA, 2015. HIV-1 Is Associated With Lower Group B Streptococcus Capsular and Surface-Protein IgG Antibody Levels and Reduced Transplacental Antibody Transfer in Pregnant Women.  J Infect Dis 212(3):453-62

Dangor Z; Kwatra G; Izu A; Lala SG; Madhi SA, 2015. Review on the association of Group B Streptococcus capsular antibody and protection against invasive disease in infants.  Expert Rev Vaccines 14(1):135-49

Lala SG; Parbhoo KB; Verwey C; Khan R; Dangor Z; Moore D; Pettifor JM; Martinson NA, 2014. The effect of topical calcipotriol or zinc on tuberculin skin tests in hospitalised South African children.  Int J Tuberc Lung Dis 18(4):388-93

Dangor Z; Izu A; Moore DP; Nunes MC; Solomon F; Beylis N; von Gottberg A; McAnerney JM; Madhi SA, 2014. Temporal association in hospitalizations for tuberculosis, invasive pneumococcal disease and influenza virus illness in South African children.  PLoS One 9(3):e91464

Madhi SA; Dangor Z; Heath PT; Schrag S; Izu A; Sobanjo-Ter Meulen A; Dull PM, 2013. Considerations for a phase-III trial to evaluate a group B Streptococcus polysaccharide-protein conjugate vaccine in pregnant women for the prevention of early- and late-onset invasive disease in young-infants.  Vaccine 31 Suppl 4:D52-7

Dangor Z; Izu A; Hillier K; Solomon F; Beylis N; Moore DP; Nunes MC; Madhi SA, 2013. Impact of the antiretroviral treatment program on the burden of hospitalization for culture-confirmed tuberculosis in South African children: a time-series analysis.  Pediatr Infect Dis J 32(9):972-7

Dangor Z; Hoff LA; Scott R, 1998. Woman abuse in South Africa: an exploratory study.  Violence Against Women 4(2):125-52

Publication list retrieved from NCBI using ImpactPubs