{"id":929,"date":"2021-03-02T09:43:12","date_gmt":"2021-03-02T07:43:12","guid":{"rendered":"https:\/\/wits-vida.org\/wordpress21\/?post_type=avada_faq&p=929"},"modified":"2023-10-10T16:16:03","modified_gmt":"2023-10-10T14:16:03","slug":"dr-renate-strehlau","status":"publish","type":"avada_faq","link":"https:\/\/wits-vida.org\/team-member\/dr-renate-strehlau\/","title":{"rendered":"Dr Renate Strehlau"},"content":{"rendered":"

<\/span><\/div>

Dr Renate Strehlau<\/h2><\/div>

Clinical Researcher<\/h4><\/div><\/div><\/div>

About<\/h4><\/div>

Dr Renate Strehlau is a clinical researcher and the deputy director of Nkanyezi, a satellite site of Wits VIDA Research Unit.<\/p>\n

Based within the Department of Paediatrics and Child Health at the Rahima Moosa Mother and Child Hospital (RMMCH), Renate manages an active research unit focused primarily on paediatric HIV treatment, novel drug development, and mother-to child HIV transmission.<\/p>\n

She has a special interest in paediatric neurodevelopment and has completed her Masters Degree on this topic. Renate participates in the teaching of undergraduate medical students and the supervision of research projects.<\/p>\n<\/div>

<\/div><\/div>
ORCiD<\/span><\/a><\/div><\/div><\/div><\/div><\/div>

Publications<\/h4><\/div>
\n\t\t\t\t\n\t\t\t\t2023<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2022<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2021<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2020<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2019<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2018<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2017<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2016<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2015<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2014<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2013<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2012<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2011<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2010<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t2009<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t1977<\/a><\/label>\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t1975<\/a><\/label>\n\n\t\t\t<\/form>

Madhi SA; Anderson AS; Absalon J; Radley D; Simon R; Jongihlati B; Strehlau R; van Niekerk AM; Izu A; Naidoo N; Kwatra G; Ramsamy Y; Said M; Jones S; Jose L; Fairlie L; Barnabas SL; Newton R; Munson S; Jefferies Z; Pavliakova D; Silmon de Monerri NC; Gomme E; Perez JL; Scott DA; Gruber WC; Jansen KU<\/span>, 2023<\/span>. Potential for Maternally Administered Vaccine for Infant Group B Streptococcus.<\/a><\/span>  N Engl J Med<\/span> 389(3):215-227<\/span><\/p>

<\/p>

Kuhn L; Wang T; Li F; Strehlau R; Tobin NH; Violari A; Brooker S; Patel F; Liberty A; Shiau S; Arpadi SM; Wadhwa S; Yin MT; Wang S; Tiemessen CT; Aldrovandi GM<\/span>, 2023<\/span>. Microbiota in the oral cavity of school-age children with HIV who started antiretroviral therapy at young ages in South Africa.<\/a><\/span>  AIDS<\/span> 37(10):1583-1591<\/span><\/p>

<\/p>

Muller WJ; Madhi SA; Seoane Nu\u00f1ez B; Baca Cots M; Bosheva M; Dagan R; Hammitt LL; Llapur CJ; Novoa JM; Saez Llorens X; Grenham A; Kelly EJ; Mankad VS; Shroff M; Takas T; Leach A; Villafana T<\/span>, 2023<\/span>. Nirsevimab for Prevention of RSV in Term and Late-Preterm Infants.<\/a><\/span>  N Engl J Med<\/span> 388(16):1533-1534<\/span><\/p>

<\/p>

Smith ER; Oakley E; Grandner GW; Ferguson K; Farooq F; Afshar Y; Ahlberg M; Ahmadzia H; Akelo V; Aldrovandi G; Tippett Barr BA; Bevilacqua E; Brandt JS; Broutet N; Fern\u00e1ndez Buhigas I; Carrillo J; Clifton R; Conry J; Cosmi E; Crispi F; Crovetto F; Delgado-L\u00f3pez C; Divakar H; Driscoll AJ; Favre G; Flaherman VJ; Gale C; Gil MM; Gottlieb SL; Gratac\u00f3s E; Hernandez O; Jones S; Kalafat E; Khagayi S; Knight M; Kotloff K; Lanzone A; Le Doare K; Lees C; Litman E; Lokken EM; Laurita Longo V; Madhi SA; Magee LA; Martinez-Portilla RJ; McClure EM; Metz TD; Miller ES; Money D; Moungmaithong S; Mullins E; Nachega JB; Nunes MC; Onyango D; Panchaud A; Poon LC; Raiten D; Regan L; Rukundo G; Sahota D; Sakowicz A; Sanin-Blair J; S\u00f6derling J; Stephansson O; Temmerman M; Thorson A; Tolosa JE; Townson J; Valencia-Prado M; Visentin S; von Dadelszen P; Adams Waldorf K; Whitehead C; Yassa M; Tielsch JM<\/span>, 2023<\/span>. Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis.<\/a><\/span>  BMJ Glob Health<\/span> 8<\/span>.<\/p>

<\/p>

Wu M; Shiau S; Strehlau R; Liberty A; Patel F; Burke M; Murnane PM; Violari A; Yin MT; Abrams EJ; Kuhn L; Arpadi S<\/span>, 2023<\/span>. Disclosure to South African children about their own HIV status over time.<\/a><\/span>  AIDS Care<\/span> 35(3):334-340<\/span><\/p>

<\/p>

Nunes MC; Jones S; Strehlau R; Baba V; Ditse Z; da Silva K; Bothma L; Serafin N; Baillie VL; Kwatra G; Burke M; Wise A; Adam M; Mlandu P; Melamu M; Phelp J; Fraser W; Wright C; Zell E; Adam Y; Madhi SA<\/span>, 2022<\/span>. Antepartum SARS-CoV-2 infection and adverse birth outcomes in South African women.<\/a><\/span>  J Glob Health<\/span> 12:05050<\/span><\/p>

<\/p>

Nunes MC; Jones S; Strehlau R; Baba V; Ditse Z; da Silva K; Bothma L; Serafin N; Baillie VL; Kwatra G; Burke M; Wise A; Adam M; Mlandu P; Melamu M; Phelp J; Fraser W; Wright C; Zell E; Adam Y; Madhi SA<\/span>, 2022<\/span>. Active Intrapartum SARS-CoV-2 Infection and Pregnancy Outcomes.<\/a><\/span>  Am J Perinatol<\/span> 39(S 01):S42-S48<\/span><\/p>

<\/p>

Roberts JA; Shen Y; Strehlau R; Patel F; Kuhn L; Coovadia A; Kaufman JJ; Shiau S; Arpadi SM; Yin MT<\/span>, 2022<\/span>. Comparison of quantitative ultrasonography and dual X-ray absorptiometry for bone status assessment in South African children living with HIV.<\/a><\/span>  PLoS One<\/span> 17(10):e0276290<\/span><\/p>

<\/p>

Ebonwu J; Lassauni\u00e8re R; Paximadis M; Strehlau R; Gray GE; Kuhn L; Tiemessen CT<\/span>, 2022<\/span>. FCGR3A gene duplication, Fc\u03b3RIIb-232TT and Fc\u03b3RIIIb-HNA1a associate with an increased risk of vertical acquisition of HIV-1.<\/a><\/span>  PLoS One<\/span> 17(9):e0273933<\/span><\/p>

<\/p>

Morris SE; Strehlau R; Shiau S; Abrams EJ; Tiemessen CT; Kuhn L; Yates AJ<\/span>, 2022<\/span>. Healthy dynamics of CD4 T cells may drive HIV resurgence in perinatally-infected infants on antiretroviral therapy.<\/a><\/span>  PLoS Pathog<\/span> 18(8):e1010751<\/span><\/p>

<\/p>

Nunes MC; Jones S; Ditse Z; da Silva K; Serafin N; Strehlau R; Wise A; Burke M; Baba V; Baillie VL; Nzimande A; Jafta N; Adam M; Mlandu P; Melamu M; Phelp J; Feldman C; Adam Y; Madhi SA; Kwatra G<\/span>, 2022<\/span>. Maternal-foetal transfer of severe acute respiratory syndrome coronavirus 2 antibodies among women with and those without HIV infection.<\/a><\/span>  AIDS<\/span> 36(13):1777-1782<\/span><\/p>

<\/p>

Potterton J; Strehlau R; Shiau S; Comley-White N; Kuhn L; Yin M; Arpadi S<\/span>, 2022<\/span>. Evaluation of submaximal endurance in young children living with HIV.<\/a><\/span>  S Afr J Physiother<\/span> 78(1):1613<\/span><\/p>

<\/p>

Domachowske J; Madhi SA; Sim\u00f5es EAF; Atanasova V; Caba\u00f1as F; Furuno K; Garcia-Garcia ML; Grantina I; Nguyen KA; Brooks D; Chang Y; Leach A; Takas T; Yuan Y; Griffin MP; Mankad VS; Villafana T<\/span>, 2022<\/span>. Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity.<\/a><\/span>  N Engl J Med<\/span> 386(9):892-894<\/span><\/p>

<\/p>

Hammitt LL; Dagan R; Yuan Y; Baca Cots M; Bosheva M; Madhi SA; Muller WJ; Zar HJ; Brooks D; Grenham A; W\u00e4hlby Hamr\u00e9n U; Mankad VS; Ren P; Takas T; Abram ME; Leach A; Griffin MP; Villafana T<\/span>, 2022<\/span>. Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.<\/a><\/span>  N Engl J Med<\/span> 386(9):837-846<\/span><\/p>

<\/p>

Kuhn L; Paximadis M; Da Costa Dias B; Shen Y; Mncube S; Strehlau R; Shiau S; Patel F; Burke M; Technau KG; Sherman G; Loubser S; Abrams EJ; Tiemessen CT<\/span>, 2022<\/span>. Predictors of Cell-Associated Human Immunodeficiency Virus (HIV)-1 DNA Over 1 Year in Very Early Treated Infants.<\/a><\/span>  Clin Infect Dis<\/span> 74(6):1047-1054<\/span><\/p>

<\/p>

Mukendi A; Kufa T; Murray T; Burke M; Strehlau R; Technau KG; Tiemessen CT; Sherman GG; Mazanderani AH<\/span>, 2021<\/span>. Evaluating the performance of the GeneXpert HIV-1 qualitative assay as a consecutive test for a new early infant diagnosis algorithm in South Africa.<\/a><\/span>  S Afr Med J<\/span> 111(9):857-861<\/span><\/p>

<\/p>

Ebonwu J; Lassauni\u00e8re R; Paximadis M; Goosen M; Strehlau R; Gray GE; Kuhn L; Tiemessen CT<\/span>, 2021<\/span>. An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition.<\/a><\/span>  Front Immunol<\/span> 12:760571<\/span><\/p>

<\/p>

Jassat W; Cohen C; Tempia S; Masha M; Goldstein S; Kufa T; Murangandi P; Savulescu D; Walaza S; Bam JL; Davies MA; Prozesky HW; Naude J; Mnguni AT; Lawrence CA; Mathema HT; Zamparini J; Black J; Mehta R; Parker A; Chikobvu P; Dawood H; Muvhango N; Strydom R; Adelekan T; Mdlovu B; Moodley N; Namavhandu EL; Rheeder P; Venturas J; Magula N; Blumberg L<\/span>, 2021<\/span>. Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study.<\/a><\/span>  Lancet HIV<\/span> 8(9):e554-e567<\/span><\/p>

<\/p>

Jassat W; Mudara C; Ozougwu L; Tempia S; Blumberg L; Davies MA; Pillay Y; Carter T; Morewane R; Wolmarans M; von Gottberg A; Bhiman JN; Walaza S; Cohen C<\/span>, 2021<\/span>. Difference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study.<\/a><\/span>  Lancet Glob Health<\/span> 9(9):e1216-e1225<\/span><\/p>

<\/p>

Shen Y; Shiau S; Strehlau R; Burke M; Patel F; Johnson CT; Rizkalla B; Dympna G; Kuhn L; Coovadia A; Yin MT; Arpadi SM<\/span>, 2021<\/span>. Persistently lower bone mass and bone turnover among South African children living with well controlled HIV.<\/a><\/span>  AIDS<\/span> 35(13):2137-2147<\/span><\/p>

<\/p>

Shiau S; Strehlau R; Shen Y; He Y; Patel F; Burke M; Abrams EJ; Tiemessen CT; Wang S; Kuhn L<\/span>, 2021<\/span>. Virologic Response to Very Early HIV Treatment in Neonates.<\/a><\/span>  J Clin Med<\/span> 10<\/span>.<\/p>

<\/p>

Shalekoff S; Loubser S; Dias BDC; Strehlau R; Shiau S; Wang S; He Y; Abrams EJ; Kuhn L; Tiemessen CT<\/span>, 2021<\/span>. Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment.<\/a><\/span>  Front Pediatr<\/span> 9:618191<\/span><\/p>

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Bezuidenhout JK; Khoza-Shangase K; De Maayer T; Strehlau R<\/span>, 2021<\/span>. Outcomes of newborn hearing screening at an academic secondary level hospital in Johannesburg, South Africa.<\/a><\/span>  S Afr J Commun Disord<\/span> 68(1):e1-e8<\/span><\/p>

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Strehlau R; Burke M; van Aswegen T; Kuhn L; Potterton J<\/span>, 2021<\/span>. Neurodevelopment in early treated HIV-infected infants participating in a developmental stimulation programme compared with controls.<\/a><\/span>  Child Care Health Dev<\/span> 47(2):154-162<\/span><\/p>

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Patel F; Shiau S; Strehlau R; Shen Y; Burke M; Paximadis M; Shalekoff S; Schramm D; Technau KG; Sherman GG; Coovadia A; Tiemessen CT; Abrams EJ; Kuhn L<\/span>, 2021<\/span>. Low Pretreatment Viral Loads in Infants With HIV in an Era of High-maternal Antiretroviral Therapy Coverage.<\/a><\/span>  Pediatr Infect Dis J<\/span> 40(1):55-59<\/span><\/p>

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Su J; Shiau S; Arpadi SM; Strehlau R; Burke M; Patel F; Kuhn L; Coovadia A; Yin MT<\/span>, 2021<\/span>. Switch to Efavirenz Attenuates Lipoatrophy in Girls With Perinatal HIV.<\/a><\/span>  J Pediatr Gastroenterol Nutr<\/span> 72(1):e15-e20<\/span><\/p>

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Shiau S; Evans H; Strehlau R; Shen Y; Burke M; Liberty A; Coovadia A; Abrams EJ; Yin MT; Violari A; Kuhn L; Arpadi SM<\/span>, 2020<\/span>. Behavioral Functioning and Quality of Life in South African Children Living with HIV on Antiretroviral Therapy.<\/a><\/span>  J Pediatr<\/span> 227:308-313.e2<\/span><\/p>

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Shiau S; Yin MT; Strehlau R; Shen J; Abrams EJ; Coovadia A; Kuhn L; Arpadi SM<\/span>, 2020<\/span>. Bone turnover markers in children living with HIV remaining on ritonavir-boosted lopinavir or switching to efavirenz.<\/a><\/span>  Bone<\/span> 138:115500<\/span><\/p>

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Morris SE; Dziobek-Garrett L; Strehlau R; Schr\u00f6ter J; Shiau S; Anelone AJN; Paximadis M; de Boer RJ; Abrams EJ; Tiemessen CT; Kuhn L; Yates AJ<\/span>, 2020<\/span>. Quantifying the Dynamics of HIV Decline in Perinatally Infected Neonates on Antiretroviral Therapy.<\/a><\/span>  J Acquir Immune Defic Syndr<\/span> 85(2):209-218<\/span><\/p>

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Strehlau R; Paximadis M; Sherman GG; Abrams EJ; Tiemessen CT; Kuhn L<\/span>, 2020<\/span>. Response to Zhao and Zhou: Diagnosis of HIV infection in breastfed infants of mothers on antiretroviral therapy.<\/a><\/span>  AIDS<\/span> 34(5):798-799<\/span><\/p>

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Shiau S; Yin MT; Strehlau R; Burke M; Patel F; Kuhn L; Coovadia A; Norris SA; Arpadi SM<\/span>, 2020<\/span>. Deficits in Bone Architecture and Strength in Children Living With HIV on Antiretroviral Therapy.<\/a><\/span>  J Acquir Immune Defic Syndr<\/span> 84(1):101-106<\/span><\/p>

<\/p>

Strehlau R; van Aswegen T; Burke M; Kuhn L; Potterton J<\/span>, 2020<\/span>. A description of early neurodevelopment in a cohort of HIV-exposed uninfected children.<\/a><\/span>  AIDS Care<\/span> 32(11):1421-1428<\/span><\/p>

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Rabie H; Tikiso T; Lee J; Fairlie L; Strehlau R; Bobat R; Liberty A; McIlleron H; Andrieux-Meyer I; Cotton M; Lallemant M; Denti P<\/span>, 2020<\/span>. Abacavir Exposure in Children Cotreated for Tuberculosis with Rifampin and Superboosted Lopinavir-Ritonavir.<\/a><\/span>  Antimicrob Agents Chemother<\/span> 64<\/span>.<\/p>

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Kuhn L; Strehlau R; Shiau S; Patel F; Shen Y; Technau KG; Burke M; Sherman G; Coovadia A; Aldrovandi GM; Hazra R; Tsai WY; Tiemessen CT; Abrams EJ<\/span>, 2020<\/span>. Early antiretroviral treatment of infants to attain HIV remission.<\/a><\/span>  EClinicalMedicine<\/span> 18:100241<\/span><\/p>

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Patel F; Thurman C; Liberty A; Burke M; Strehlau R; Shiau S; Coovadia A; Abrams EJ; Violari A; Kuhn L<\/span>, 2020<\/span>. Negative Diagnostic PCR Tests in School-Aged, HIV-Infected Children on Antiretroviral Therapy Since Early Life in Johannesburg, South Africa.<\/a><\/span>  J Acquir Immune Defic Syndr<\/span> 83(4):381-389<\/span><\/p>

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Shiau S; Arpadi SM; Burke M; Liberty A; Thurman C; Patel F; Strehlau R; Abrams EJ; Coovadia A; Violari A; Kuhn L<\/span>, 2020<\/span>. Educational delays among children living with perinatally-acquired HIV in Johannesburg, South Africa.<\/a><\/span>  AIDS Care<\/span> 32(4):438-444<\/span><\/p>

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Shen J; Liberty A; Shiau S; Strehlau R; Pierson S; Patel F; Wang L; Burke M; Violari A; Coovadia A; Abrams EJ; Arpadi S; Foca M; Kuhn L<\/span>, 2020<\/span>. Mitochondrial Impairment in Well-Suppressed Children with Perinatal HIV-Infection on Antiretroviral Therapy.<\/a><\/span>  AIDS Res Hum Retroviruses<\/span> 36(1):27-38<\/span><\/p>

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Arpadi SM; Thurman CB; Patel F; Kaufman JJ; Strehlau R; Burke M; Shiau S; Coovadia A; Yin MT<\/span>, 2019<\/span>. Bone Quality Measured Using Calcaneal Quantitative Ultrasonography Is Reduced Among Children with HIV in Johannesburg, South Africa.<\/a><\/span>  J Pediatr<\/span> 215:267-271.e2<\/span><\/p>

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Desmonde S; Frank SC; Coovadia A; Dahourou DL; Hou T; Abrams EJ; Amorissani-Folquet M; Walensky RP; Strehlau R; Penazzato M; Freedberg KA; Kuhn L; Leroy V; Ciaranello AL<\/span>, 2019<\/span>. Cost-Effectiveness of Preemptive Switching to Efavirenz-Based Antiretroviral Therapy for Children With Human Immunodeficiency Virus.<\/a><\/span>  Open Forum Infect Dis<\/span> 6(7):ofz276<\/span><\/p>

<\/p>

Shiau S; Strehlau R; Wang S; Violari A; Do C; Patel F; Liberty A; Krupska I; Arpadi SM; Foca M; Coovadia A; Abrams EJ; Tycko B; Terry MB; Kuhn L<\/span>, 2019<\/span>. Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy.<\/a><\/span>  Sci Rep<\/span> 9(1):10495<\/span><\/p>

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Strehlau R; Paximadis M; Patel F; Burke M; Technau KG; Shiau S; Abrams EJ; Sherman GG; Hunt G; Ledwaba J; Mazanderani AH; Tiemessen CT; Kuhn L<\/span>, 2019<\/span>. HIV diagnostic challenges in breast-fed infants of mothers on antiretroviral therapy.<\/a><\/span>  AIDS<\/span> 33(11):1751-1756<\/span><\/p>

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Haeri Mazanderani A; Kufa T; Technau KG; Strehlau R; Patel F; Shiau S; Burke M; Kuhn L; Abrams EJ; Sherman GG<\/span>, 2019<\/span>. Early infant diagnosis HIV-1 PCR cycle-threshold predicts infant viral load at birth.<\/a><\/span>  J Clin Virol<\/span> 114:21-25<\/span><\/p>

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Technau KG; Strehlau R; Patel F; Shiau S; Burke M; Conradie M; Sorour G; Sherman GG; Coovadia A; Murnane PM; Abrams EJ; Kuhn L<\/span>, 2018<\/span>. 12-month outcomes of HIV-infected infants identified at birth at one maternity site in Johannesburg, South Africa: an observational cohort study.<\/a><\/span>  Lancet HIV<\/span> 5(12):e706-e714<\/span><\/p>

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Shiau S; Strehlau R; Shen J; Violari A; Patel F; Liberty A; Foca M; Wang S; Terry MB; Yin MT; Coovadia A; Abrams EJ; Arpadi SM; Kuhn L<\/span>, 2018<\/span>. Biomarkers of Aging in HIV-Infected Children on Suppressive Antiretroviral Therapy.<\/a><\/span>  J Acquir Immune Defic Syndr<\/span> 78(5):549-556<\/span><\/p>

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Kuhn L; Paximadis M; Da Costa Dias B; Loubser S; Strehlau R; Patel F; Shiau S; Coovadia A; Abrams EJ; Tiemessen CT<\/span>, 2018<\/span>. Age at antiretroviral therapy initiation and cell-associated HIV-1 DNA levels in HIV-1-infected children.<\/a><\/span>  PLoS One<\/span> 13(4):e0195514<\/span><\/p>

<\/p>

Strehlau R; van Aswegen T; Potterton J<\/span>, 2018<\/span>. Neurodevelopmental assessment of HIV-exposed uninfected and early-treated HIV-infected children: study protocol.<\/a><\/span>  BMC Res Notes<\/span> 11(1):235<\/span><\/p>

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Shiau S; Yin MT; Strehlau R; Patel F; Mbete N; Kuhn L; Coovadia A; Arpadi SM<\/span>, 2018<\/span>. Decreased bone turnover in HIV-infected children on antiretroviral therapy.<\/a><\/span>  Arch Osteoporos<\/span> 13(1):40<\/span><\/p>

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Strehlau R; Shiau S; Arpadi S; Patel F; Pinillos F; Tsai WY; Coovadia A; Abrams E; Kuhn L<\/span>, 2018<\/span>. Substituting Abacavir for Stavudine in Children Who Are Virally Suppressed Without Lipodystrophy: Randomized Clinical Trial in Johannesburg, South Africa.<\/a><\/span>  J Pediatric Infect Dis Soc<\/span> 7(3):e70-e77<\/span><\/p>

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Murnane PM; Strehlau R; Shiau S; Patel F; Mbete N; Hunt G; Abrams EJ; Coovadia A; Kuhn L<\/span>, 2018<\/span>. Reply to Van de Wijer et al.<\/a><\/span>  Clin Infect Dis<\/span> 66(7):1151-1152<\/span><\/p>

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Ramteke SM; Shiau S; Foca M; Strehlau R; Pinillos F; Patel F; Violari A; Liberty A; Coovadia A; Kuhn L; Arpadi SM<\/span>, 2018<\/span>. Patterns of Growth, Body Composition, and Lipid Profiles in a South African Cohort of Human Immunodeficiency Virus-Infected and Uninfected Children: A Cross-Sectional Study.<\/a><\/span>  J Pediatric Infect Dis Soc<\/span> 7(2):143-150<\/span><\/p>

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Technau KG; Mazanderani AH; Kuhn L; Hans L; Strehlau R; Abrams EJ; Conradie M; Coovadia A; Mbete N; Murnane PM; Patel F; Shiau S; Tiemessen CT; Sherman GG<\/span>, 2017<\/span>. Prevalence and outcomes of HIV-1 diagnostic challenges during universal birth testing - an urban South African observational cohort.<\/a><\/span>  J Int AIDS Soc<\/span> 20(Suppl 6):21761<\/span><\/p>

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Murnane PM; Strehlau R; Shiau S; Patel F; Mbete N; Hunt G; Abrams EJ; Coovadia A; Kuhn L<\/span>, 2017<\/span>. Switching to Efavirenz Versus Remaining on Ritonavir-boosted Lopinavir in Human Immunodeficiency Virus-infected Children Exposed to Nevirapine: Long-term Outcomes of a Randomized Trial.<\/a><\/span>  Clin Infect Dis<\/span> 65(3):477-485<\/span><\/p>

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Shiau S; Webber A; Strehlau R; Patel F; Coovadia A; Kozakowski S; Brodlie S; Yin MT; Kuhn L; Arpadi SM<\/span>, 2017<\/span>. Dietary Inadequacies in HIV-infected and Uninfected School-aged Children in Johannesburg, South Africa.<\/a><\/span>  J Pediatr Gastroenterol Nutr<\/span> 65(3):332-337<\/span><\/p>

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Shiau S; Strehlau R; Technau KG; Patel F; Arpadi SM; Coovadia A; Abrams EJ; Kuhn L<\/span>, 2017<\/span>. Early age at start of antiretroviral therapy associated with better virologic control after initial suppression in HIV-infected infants.<\/a><\/span>  AIDS<\/span> 31(3):355-364<\/span><\/p>

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Murnane PM; Sigamoney SL; Pinillos F; Shiau S; Strehlau R; Patel F; Liberty A; Abrams EJ; Arpadi S; Coovadia A; Violari A; Kuhn L<\/span>, 2017<\/span>. Extent of disclosure: what perinatally HIV-infected children have been told about their own HIV status.<\/a><\/span>  AIDS Care<\/span> 29(3):378-386<\/span><\/p>

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Ramteke SM; Kaufman JJ; Arpadi SM; Shiau S; Strehlau R; Patel F; Mbete N; Coovadia A; Yin MT<\/span>, 2017<\/span>. Unusually High Calcaneal Speed of Sound Measurements in\u00a0Children with Small Foot Size.<\/a><\/span>  Ultrasound Med Biol<\/span> 43(1):357-361<\/span><\/p>

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Fowler MG; Qin M; Fiscus SA; Currier JS; Flynn PM; Chipato T; McIntyre J; Gnanashanmugam D; Siberry GK; Coletti AS; Taha TE; Klingman KL; Martinson FE; Owor M; Violari A; Moodley D; Theron GB; Bhosale R; Bobat R; Chi BH; Strehlau R; Mlay P; Loftis AJ; Browning R; Fenton T; Purdue L; Basar M; Shapiro DE; Mofenson LM<\/span>, 2016<\/span>. Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention.<\/a><\/span>  N Engl J Med<\/span> 375(18):1726-1737<\/span><\/p>

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Strehlau R; Kuhn L; Abrams EJ; Coovadia A<\/span>, 2016<\/span>. HIV-associated neurodevelopmental delay: prevalence, predictors and persistence in relation to antiretroviral therapy initiation and viral suppression.<\/a><\/span>  Child Care Health Dev<\/span> 42(6):881-889<\/span><\/p>

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Arpadi SM; Shiau S; Strehlau R; Patel F; Mbete N; McMahon DJ; Kaufman JJ; Coovadia A; Kuhn L; Yin MT<\/span>, 2016<\/span>. Efavirenz is associated with higher bone mass in South African children with HIV.<\/a><\/span>  AIDS<\/span> 30(16):2459-2467<\/span><\/p>

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Moholisa RR; Schomaker M; Kuhn L; Castel S; Wiesner L; Coovadia A; Strehlau R; Patel F; Pinillos F; Abrams EJ; Maartens G; McIlleron H<\/span>, 2016<\/span>. Effect of Lopinavir and Nevirapine Concentrations on Viral Outcomes in Protease Inhibitor-experienced HIV-infected Children.<\/a><\/span>  Pediatr Infect Dis J<\/span> 35(12):e378-e383<\/span><\/p>

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Wong M; Shiau S; Yin MT; Strehlau R; Patel F; Coovadia A; Micklesfield LK; Kuhn L; Arpadi SM<\/span>, 2016<\/span>. Decreased Vigorous Physical Activity in School-Aged Children with Human Immunodeficiency Virus in Johannesburg, South Africa.<\/a><\/span>  J Pediatr<\/span> 172:103-9<\/span><\/p>

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Potterton J; Hilburn N; Strehlau R<\/span>, 2016<\/span>. Developmental status of preschool children receiving cART: a descriptive cohort study.<\/a><\/span>  Child Care Health Dev<\/span> 42(3):410-4<\/span><\/p>

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Pinillos F; Dandara C; Swart M; Strehlau R; Kuhn L; Patel F; Coovadia A; Abrams E<\/span>, 2016<\/span>. Case report: Severe central nervous system manifestations associated with aberrant efavirenz metabolism in children: the role of CYP2B6 genetic variation.<\/a><\/span>  BMC Infect Dis<\/span> 16:56<\/span><\/p>

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Coovadia A; Abrams EJ; Strehlau R; Shiau S; Pinillos F; Martens L; Patel F; Hunt G; Tsai WY; Kuhn L<\/span>, 2015<\/span>. Efavirenz-Based Antiretroviral Therapy Among Nevirapine-Exposed HIV-Infected Children in South Africa: A Randomized Clinical Trial.<\/a><\/span>  JAMA<\/span> 314(17):1808-17<\/span><\/p>

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Strehlau R; Donati AP; Arce PM; Lissens J; Yang R; Biguenet S; Cambilargiu D; Hardy H; Correll T<\/span>, 2015<\/span>. PRINCE-1: safety and efficacy of atazanavir powder and ritonavir liquid in HIV-1-infected antiretroviral-na\u00efve and -experienced infants and children aged \u22653 months to <6 years.<\/a><\/span>  J Int AIDS Soc<\/span> 18(1):19467<\/span><\/p>

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Giandhari J; Basson AE; Coovadia A; Kuhn L; Abrams EJ; Strehlau R; Morris L; Hunt GM<\/span>, 2015<\/span>. Genetic Changes in HIV-1 Gag-Protease Associated with Protease Inhibitor-Based Therapy Failure in Pediatric Patients.<\/a><\/span>  AIDS Res Hum Retroviruses<\/span> 31(8):776-82<\/span><\/p>

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Kuhn L; Schramm DB; Shiau S; Strehlau R; Pinillos F; Technau K; Coovadia A; Abrams EJ; Puren A; Tiemessen CT<\/span>, 2015<\/span>. Young age at start of antiretroviral therapy and negative HIV antibody results in HIV-infected children when suppressed.<\/a><\/span>  AIDS<\/span> 29(9):1053-60<\/span><\/p>

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Hunt GM; Morris L; Moorthy A; Coovadia A; Abrams EJ; Strehlau R; Kuhn L; Persaud D<\/span>, 2014<\/span>. Concordance between allele-specific PCR and ultra-deep pyrosequencing for the detection of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations.<\/a><\/span>  J Virol Methods<\/span> 207:182-7<\/span><\/p>

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Technau KG; Kalk E; Coovadia A; Black V; Pickerill S; Mellins CA; Abrams EJ; Strehlau R; Kuhn L<\/span>, 2014<\/span>. Timing of maternal HIV testing and uptake of prevention of mother-to-child transmission interventions among women and their infected infants in Johannesburg, South Africa.<\/a><\/span>  J Acquir Immune Defic Syndr<\/span> 65(5):e170-8<\/span><\/p>

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Shiau S; Kuhn L; Strehlau R; Martens L; McIlleron H; Meredith S; Wiesner L; Coovadia A; Abrams EJ; Arpadi SM<\/span>, 2014<\/span>. Sex differences in responses to antiretroviral treatment in South African HIV-infected children on ritonavir-boosted lopinavir- and nevirapine-based treatment.<\/a><\/span>  BMC Pediatr<\/span> 14:39<\/span><\/p>

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Moholisa RR; Schomaker M; Kuhn L; Meredith S; Wiesner L; Coovadia A; Strehlau R; Martens L; Abrams EJ; Maartens G; McIlleron H<\/span>, 2014<\/span>. Plasma lopinavir concentrations predict virological failure in a cohort of South African children initiating a protease-inhibitor-based regimen.<\/a><\/span>  Antivir Ther<\/span> 19(4):399-406<\/span><\/p>

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Technau KG; Lazarus E; Kuhn L; Abrams EJ; Sorour G; Strehlau R; Reubenson G; Davies MA; Coovadia A<\/span>, 2013<\/span>. Poor early virologic performance and durability of abacavir-based first-line regimens for HIV-infected children.<\/a><\/span>  Pediatr Infect Dis J<\/span> 32(8):851-5<\/span><\/p>

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Shiau S; Arpadi S; Strehlau R; Martens L; Patel F; Coovadia A; Abrams EJ; Kuhn L<\/span>, 2013<\/span>. Initiation of antiretroviral therapy before 6 months of age is associated with faster growth recovery in South African children perinatally infected with human immunodeficiency virus.<\/a><\/span>  J Pediatr<\/span> 162(6):1138-45, 1145.e1-2<\/span><\/p>

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Teasdale CA; Abrams EJ; Coovadia A; Strehlau R; Martens L; Kuhn L<\/span>, 2013<\/span>. Adherence and viral suppression among infants and young children initiating protease inhibitor-based antiretroviral therapy.<\/a><\/span>  Pediatr Infect Dis J<\/span> 32(5):489-94<\/span><\/p>

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Arpadi S; Shiau S; Strehlau R; Martens L; Patel F; Coovadia A; Abrams EJ; Kuhn L<\/span>, 2013<\/span>. Metabolic abnormalities and body composition of HIV-infected children on Lopinavir or Nevirapine-based antiretroviral therapy.<\/a><\/span>  Arch Dis Child<\/span> 98(4):258-64<\/span><\/p>

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Kuhn L; Coovadia A; Strehlau R; Martens L; Hu CC; Meyers T; Sherman G; Hunt G; Persaud D; Morris L; Tsai WY; Abrams EJ<\/span>, 2012<\/span>. Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial.<\/a><\/span>  Lancet Infect Dis<\/span> 12(7):521-30<\/span><\/p>

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Strehlau R; Coovadia A; Abrams EJ; Martens L; Arpadi S; Meyers T; Kuhn L<\/span>, 2012<\/span>. Lipid profiles in young HIV-infected children initiating and changing antiretroviral therapy.<\/a><\/span>  J Acquir Immune Defic Syndr<\/span> 60(4):369-76<\/span><\/p>

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Strehlau R; Martens L; Coovadia A; Dandara C; Norman J; Maisel J; Kuhn L; Abrams EJ<\/span>, 2011<\/span>. Absence seizures associated with efavirenz initiation.<\/a><\/span>  Pediatr Infect Dis J<\/span> 30(11):1001-3<\/span><\/p>

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Taylor BS; Hunt G; Abrams EJ; Coovadia A; Meyers T; Sherman G; Strehlau R; Morris L; Kuhn L<\/span>, 2011<\/span>. Rapid development of antiretroviral drug resistance mutations in HIV-infected children less than two years of age initiating protease inhibitor-based therapy in South Africa.<\/a><\/span>  AIDS Res Hum Retroviruses<\/span> 27(9):945-56<\/span><\/p>

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Moorthy A; Kuhn L; Coovadia A; Meyers T; Strehlau R; Sherman G; Tsai WY; Chen YH; Abrams EJ; Persaud D<\/span>, 2011<\/span>. Induction therapy with protease-inhibitors modifies the effect of nevirapine resistance on virologic response to nevirapine-based HAART in children.<\/a><\/span>  Clin Infect Dis<\/span> 52(4):514-21<\/span><\/p>

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Reitz C; Coovadia A; Ko S; Meyers T; Strehlau R; Sherman G; Kuhn L; Abrams EJ<\/span>, 2010<\/span>. Initial response to protease-inhibitor-based antiretroviral therapy among children less than 2 years of age in South Africa: effect of cotreatment for tuberculosis.<\/a><\/span>  J Infect Dis<\/span> 201(8):1121-31<\/span><\/p>

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Smith K; Kuhn L; Coovadia A; Meyers T; Hu CC; Reitz C; Barry G; Strehlau R; Sherman G; Abrams EJ<\/span>, 2009<\/span>. Immune reconstitution inflammatory syndrome among HIV-infected South African infants initiating antiretroviral therapy.<\/a><\/span>  AIDS<\/span> 23(9):1097-107<\/span><\/p>

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Kessler M; H\u00f6per J; Sch\u00e4fer D; Strehlau R<\/span>, 1977<\/span>. Measurements of extracellular and of interstitial cation activity (pK, pNa, pCa) with ion-selective electrodes.<\/a><\/span>  Bibl Anat<\/span>.<\/p>

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Krumme BA; Strehlau R; Kessler M<\/span>, 1975<\/span>. Proceedings: Hydrogen clearance measurements on the liver surface in situ with the multiwire electrode.<\/a><\/span>  Arzneimittelforschung<\/span> 25(10):1670-1<\/span><\/p>

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Messmer K; Kessler M; Krumme BA; H\u00f6per J; Strehlau R; Briggs D; Smiedeck P; Spetzler R<\/span>, 1975<\/span>. Proceedings: Microcirculatory changes during normovolemic hemodilution.<\/a><\/span>  Arzneimittelforschung<\/span> 25(10):1670<\/span><\/p>

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Publication list retrieved from NCBI<\/a> using ImpactPubs<\/a><\/p>.<\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"

A clinical researcher at the Vaccines and Infectious Diseases Analytics (VIDA) Research Unit.<\/p>\n","protected":false},"author":1,"featured_media":830,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"rank_math_lock_modified_date":false,"footnotes":""},"faq_category":[44],"class_list":["post-929","avada_faq","type-avada_faq","status-publish","format-standard","has-post-thumbnail","hentry","faq_category-researchers"],"acf":[],"_links":{"self":[{"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/avada_faq\/929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/avada_faq"}],"about":[{"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/types\/avada_faq"}],"author":[{"embeddable":true,"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/comments?post=929"}],"version-history":[{"count":8,"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/avada_faq\/929\/revisions"}],"predecessor-version":[{"id":4278,"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/avada_faq\/929\/revisions\/4278"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/media\/830"}],"wp:attachment":[{"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/media?parent=929"}],"wp:term":[{"taxonomy":"faq_category","embeddable":true,"href":"https:\/\/wits-vida.org\/wp-json\/wp\/v2\/faq_category?post=929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}