Negative Diagnostic PCR Tests in School-Aged, HIV- Infected Children on Antiretroviral Therapy Since Early Life in Johannesburg, South Africa.
Background: Younger age at antiretroviral therapy (ART) initiation has been associated with smaller HIV reservoirs. We investigated whether younger age of ART initiation is associated with testing negative and weaker signal on a standard HIV diagnostic test in treated children.
Author List: Patel F, Thurman C, Liberty A, Burke M, Strehlau R, Shiau S, Coovadia A, Abrams EJ, Violari A, Kuhn L.
Journal Name: J Acquir Immune Defic Syndr. 2020 Apr 1;83(4):381-389. doi: 10.1097/QAI.0000000000002265. PMID: 31913997; PMCID: PMC7462386.