Project Description

Evaluation of Intussusception After Oral Monovalent Rotavirus Vaccination in South Africa

Background: Postlicensure studies have shown an association between rotavirus vaccination and intussusception. We assessed the risk of intussusception associated with Rotarix (RV1) administration, at 6 and 14 weeks of age, in an upper-middle-income country, South Africa.

Author List: Groome MJ, Tate JE, Arnold M, Chitnis M, Cox S, de Vos C, Kirsten M, le Grange SM, Loveland J, Machaea S, Maharaj A, Andrews N, Madhi SA, Parashar UD.

Journal Name: Clin Infect Dis. 2020 Apr 10;70(8):1606-1612. doi: 10.1093/cid/ciz431. PMID: 31125061; PMCID: PMC7146001.

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