Project Description

Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines.

Background: We investigated the effect of in utero HIV-exposure, timing of antiretroviral treatment (ART) initiation, and ART interruption on memory responses and persistence of immunity induced by pneumococcal (PCV) and Haemophilus influenzae type b (HibCV) polysaccharide-protein conjugate vaccines.

Author List: Madhi SA, Izu A, Violari A, Cotton MF, Jean-Philippe P, Otwombe K, Adrian PV; CIPRA 4 team.

Journal Name: Vaccine. 2020 Mar 10;38(12):2651-2659. doi: 10.1016/j.vaccine.2020.02.026. Epub 2020 Feb 15. PMID: 32070681.

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