A prospective case-control study on the association of Rhinovirus nasopharyngeal viral load and viremia in South African children hospitalized with severe pneumonia.
Background: Rhinovirus (RV) role in pathogenesis of severe childhood disease remains controversial. We aimed to explore the association between RV molecular subtyping, nasopharyngeal viral loads and viremia with childhood pneumonia. Nasopharyngeal and blood samples from cases and controls were tested for RV and the 5′ non-coding region sequenced.
Author List: Baillie VL, Moore DP, Mathunjwa A, Morailane P, Simões EAF, Madhi SA.
Journal Name: J Clin Virol. 2020 Apr;125:104288. doi: 10.1016/j.jcv.2020.104288. Epub 2020 Feb 11. PMID: 32092643; PMCID: PMC7086148.